توضیحات

Mutation analysis of CACNA1A gene in Iranian migrainous and review literatures

Rokhsareh Meamar, Maryam Ostadsharif, Mohammad Saadatnia, Abbas Ghorbani, Nayereh Nouri, Leila Dehghani, Mansoor Salehi

Abstract

There are contrary results about the role of CACNA1A gene in the causation of common migraine in different populations. However, migraine may be genetically heterogeneous and more studies in different families and populations are required for a definite conclusion. The aim of this study was to surveyed leukocyte genomic DNA mutation of CACNA1A in Iranian migraine patients with [MA] and without aura [MO] who has family history of migraine and we performed a narrative review of all studies that evaluated CACNA1A gene, non-hemiplegic migraine [MA and MO] and FHM [familial hemiplegic migraine

Keywords: CACNA1A gene, linkage, migraine, mutation